Locations

Pallet Town: send-off gifts (one per starter, before Viridian)Pallet Town: Lance's visit home (after the final Hall of Fame)

Viridian City: the would-be professor's quizViridian City: the Meowth thief (Charmander starters only)

Route 2: the Rocket warehouse Poké Ball (starter-dependent gift)Route 2 East: the abandoned Charmander (Pikachu starters only)

Replacement for lent Pidgeot. Pikachu starter only. Lend your own Pidgeot after the Volcano Badge but before the Earth Badge or becoming Champion; keep at least one other Pokémon. After entering the Hall of Fame, return with a free party slot to receive a fixed Lv. 20 replacement Pidgeot. The original Pidgeot is not returned: its level, moves, EVs and held item are lost.

Viridian Forest: the runaway Snubbull ($20,000, one-time choice)Viridian Forest: the flower garden and the Spearow (missable)

Pewter City: Sitrus Berries → Hard Stone → TM69Pewter City: finding Brock (the Gym Leader's errands)

Route 3: the old painter's Ralts (Fresh Water errand; before the Cascade Badge)Route 3: the Scyther chase (Charmander starters) / Bug Catcher Kenji (others)

Mt. Moon: what opens the fake guards' roadblockMt. Moon: the fossil seller

Route 24 / Cerulean City: the burglary case → TM Case → TM28 DigCerulean City: King's Rock for TM04

Route 24 / Cerulean City: the burglary case → TM Case → TM28 Dig

Route 25: Nugget Bridge's "tasty treat" (say No)Route 25: the Cerulean Cape Battle Festival (quiz and placing)

Route 5: the Pokémon shelter raid (after the Cascade Badge)Underground Path: the underground battle (story, Cascade Badge)

Underground Path: the underground battle (story, Cascade Badge)

Vermilion City: feed the Wingull and the HorseaVermilion City: after the construction-site clash

S.S. Anne: Teddiursa's honey and the salt (starts the party)S.S. Anne: the party battles and the missing Teddiursa

Diglett's Cave: the warm stone in the statue (after the Silver Conference)

Route 11: the Swablu from the shelterRoute 11: cut the grass or save it (choose a side)

Route 9: the Squirtle Squad steals your Pokédex (Pikachu starters only)Route 9: the Butterfree girl (release it or keep it)

Route 10 / Lavender Town: the girl who waits (the Lavender curse)

Rock Tunnel: hide-and-seek (find four hidden kids)Rock Tunnel: Regirock, Regice and Registeel (League HQ investigation)

Power Plant: Zapdos and the ecologist

Route 10 / Lavender Town: the girl who waits (the Lavender curse)Pokémon Tower: side battles and extras

Route 8: Persian and Skitty (the quarrelling owners)

Route 7: Misty's sparring match (what closes the Bicycle offer)

Misty’s Gyarados (kept permanently). Male player with Bulbasaur starter only. Misty offers this Lv. 20 Gyarados during the Celadon gatehouse rescue, after her Starmie is wounded. Have a free party slot; if your party is full, speak to Misty again. She lets you keep it at the end of the Celadon story.

Celadon Department Store 5F: Erika's perfume question (male players)Celadon Gym: sneaking in dressed as a girl (if you insulted Erika)

Route 16 → Cycling Road → Route 18: the Secret Potion for the Warden's Dragonair

Route 16 → Cycling Road → Route 18: the Secret Potion for the Warden's DragonairCycling Road: join the Kanto Speed Alliance or drive it out

Route 16 → Cycling Road → Route 18: the Secret Potion for the Warden's DragonairRoute 18: Lara and the Tauros (unlocks the battle marathon)

Fuchsia Gym: the fake Kogas and the ninja bell (the Soul Badge trial)Fuchsia Forest: Koga's disciples

Resort Zone (Johto): the broke backpackerResort Zone: Misty's date, the Pal Park and the Couples Double Battle

Route 12: wake the Snorlax (Poké Flute)Route 12: Prof. Birch's Torchic (missable)

Route 13: the Southeast League (eight representatives and a Champion)

Route 15 → Route 14: the Cape Battle Marathon (missable)Route 14: show her a Chansey

Route 15 → Route 14: the Cape Battle Marathon (missable)Route 15: Mack the magician's "show" (talk to the empty-wallet man first)

Celadon Condominiums → Silph Co. 5F: Grandma's treats for Shota (Master Ball; missable)Silph Co. (Saffron takeover): the employee's Lapras (missable)

Rotom's Room (Silph Co.): change Rotom's form

Route 19: the surfing Pikachu (Pidgeot lead → Surf for Pikachu)

Seafoam Islands: the ice walls, Articuno and the researcher (TM14 Blizzard)Seafoam Islands: Team Rocket and Kyogre (League HQ investigation), and catching Kyogre

Route 21: break the wild Mr. Mime's barrier (unlocks Iron Head)

Cinnabar Island: finding the hidden Gym (the riddle restaurant)Cinnabar Island: the Detrick lab lockdown (door puzzle) and Mewtwo

Victory Road: "Which one is the real Blue?"Victory Road 1F: the fake item ball (Lv. 70 Electrode)

Indigo Plateau: the Indigo Conference main tournament and the "who do you cheer for?" choice (romance)Indigo Plateau (final chapter): Mewtwo joins you (take it before the Elite Four)

Pokémon League (final chapter): the Elite Four rooms under Team Rocket

Route 26: the Phanpy trainer's Nugget (sell for $30,000 or give for TM41)Route 26: the item quiz in the weekday siblings' house (→ TM43)

Route 27 → Ecruteak City: the outpost guard's letter to Momo (before the Mineral Badge)Route 27: the musician's song or battle (→ Soothe Bell)

Tohjo Falls: the hermit in the hidden room (→ TM52)

Mt. Silver lodge: the rehabilitation (how to move it along)Mt. Silver: the Turtwig owner's four-leaf clover

Cerulean Cave: Giovanni's duel and the Charizardite

New Bark Town Guesthouse: the Sinnoh traveller's quiz (→ Shinx)New Bark Town: show Prof. Elm all eight Johto Badges (→ Rare Candy, PP Max)

Route 29: Casey's Pokéathlon question (→ Electirizer)Route 29: Uncle Apricorn wants Kurt's Apricorn Box (say No twice)

Cherrygrove City: the Berry Pots girl (→ 6 PP Up; one chance)Cherrygrove City: the Wooper and the lost Poké Ball (→ Focus Band)

Route 30: the Stantler roadblock (Noctowl's Foresight)Route 30 → Route 31: the wild Chikorita that challenges Trainers (catch it; one chance)

Route 30 → Route 31: the wild Chikorita that challenges Trainers (catch it; one chance)Route 31: give Crystal your Flash TM (the way into Dark Cave)

Dark Cave: the Griseous Orb returns (after the final Hall of Fame entry)

Violet City: Tamao and Crystal (before the Sprout Tower ceremony)Violet City: the S.S. Anne passenger and his girlfriend (only if you saved the S.S. Anne)

Sprout Tower: the monks' toll (pay or fight)Sprout Tower: optional battles (Gold, the S.S. Anne monk, the Elder)

Route 32: the Hoppip blown away by the storm (→ Hurricane tutor)Route 32: the fire-breather's Fire-only battle (→ TM50 Overheat)

Ruins of Alph: the missing Molly (story chapter; how to move it along)Ruins of Alph: the girl who saw her own face (→ Rock Incense)

Union Cave 1F: Goh and the wild Cyndaquil (before you finish the Ilex Forest story)Union Cave 1F: the Zubat boy's evolution question (one gift)

Route 33: the rain-team Ace Trainer (→ 5 Dive Balls)

Azalea Town: the Slowpoke quiz (→ King's Rock)Azalea Town: the data-obsessed Super Nerd (→ TM77 Psych Up)

Ilex Forest: Bugsy's bug hunt with Honey (story; the more you catch, the better the reward)Ilex Forest: Koume, the Kimono Girl who lost her way (blocks the exit to Route 34)

Route 34: Totodile, the dance master (one chance)Route 34: advice for Whitney's victim (→ Razor Claw)

Goldenrod Magnet Train Station: Prof. Rowan's Chimchar (missable; before the Plain Badge)Goldenrod City: Goh and the Lopunny owner (win with Normal types only)

Radio Tower → Goldenrod Tunnel: Mary's secret photos (→ Cherish Ball; missable)

Dream World: Cresselia and Darkrai (post-game)

Radio Tower 4F → Goldenrod Gym: the Plain Badge, two waysRadio Tower → Goldenrod Tunnel: Mary's secret photos (→ Cherish Ball; missable)

Route 35: the Shuckle juice-maker wants a Jigglypuff (→ 2 Lum Berries)Route 35: the Pidgey with a letter (starts a chain in Ecruteak City)

National Park → Route 35: "the girl on a date with an old man" (→ 3 Heart Mail)Route 36 gatehouse → National Park: the mother and the "puppy love" (two endings)

Route 36 gatehouse → National Park: the mother and the "puppy love" (two endings)Route 36: the odd tree (after the Plain Badge)

Route 27 → Ecruteak City: the outpost guard's letter to Momo (before the Mineral Badge)Ecruteak Gym: Morty's Ghost challenge (the Fog Badge)

Burned Tower → Bell Tower gate: bring Morty to the Marauder (story; the gate quiz)Burned Tower: Prof. Hale, Molly and the three beasts (post-game; frees Entei, Suicune, Raikou)

Burned Tower → Bell Tower gate: bring Morty to the Marauder (story; the gate quiz)Bell Tower: Ho-Oh is stolen (League HQ round 4; continues Pokémon League, Mt. Silver and New Bark Town's League HQ entry)

Route 38: the Murkrow that stole a coin (Nugget trap; → 2 Rare Candies, 2 Lava Cookies or keep the Amulet Coin)Route 38 → Olivine City: small extras

Route 39: the "Team Rocket grunt" who wants $10,000 (optional Lv. 62–65 battle)Route 39: the Donphan owner who needs a Protector (→ Power Weight)

Olivine City: the Star-Chaser Sisters (talk to them from the middle)Olivine City: Sitrus Berries → Machine Part → Diving Suit → HM05 Whirlpool (with a Tentacool)

Olivine Lighthouse: medicine for Amphy (→ TM91 Flash Cannon)

Route 40: the Rhydon that can Surf (→ 2 Heavy Balls)Route 40 / Route 41: small extras

Frontier Access: the damaged stone and Jirachi (after the final Hall of Fame)Frontier Access Pokémon Center: the psychic's memory battles (after the final Hall of Fame)

Battle Frontier: small extras

Battle Tower partner room: teaming up with Yellow or Misty (continuation of Ilex Forest and Goldenrod City's romance entry; in practice unavailable)

Route 41 → Cianwood City: the Whirl Islands Challenge (quiz and battle on four islands)Route 40 / Route 41: small extras

Cianwood Pharmacy: getting the Secret Potion (continues Radio Tower, Ecruteak City and Olivine City's "Olivine Lighthouse: medicine for Amphy")Route 41 → Cianwood City: the Whirl Islands Challenge (quiz and battle on four islands)

Whirl Islands: catch Lugia (after the final Hall of Fame)

Route 42 gatehouse (Ecruteak side): the tourist crowdRoute 42: small extras

Alto Mare Waters / Mt. Mortar: small extrasMt. Mortar: the runaway Hitmontop and the Hiker's map (→ HM08 Rock Climb)

Boot Camp Ruins: the Team Rocket PC password (story; Mahogany Rocket base chapter)

Mahogany Town → Team Rocket HQ: the radio-wave investigation (story; where to go next)Mahogany Gym: Pryce's no-weather Double Battle (the Glacier Badge)

Mahogany Town → Team Rocket HQ: the radio-wave investigation (story; where to go next)Team Rocket HQ B3F: the two passwords and the Secret Key door (continues Battle Frontier, Cianwood City and Mahogany Town's "Mahogany Town → Team Rocket HQ")

Lake of Rage: the red Gyarados and the radio transmitters (story; how to move on)Lake of Rage: Petrel at the lake guardian's house (League HQ round 4; continues Pokémon League, Mt. Silver and New Bark Town's League HQ entry)

Route 43: a Chesto Berry for the listless Sentret (→ 2 Lum Berries; before the Rocket HQ is cleared)Route 43: break up the Pidgeot and Noctowl flock (→ Sharp Beak; after the Rocket HQ)

Route 44 → Ice Path: the Cleffa con man (→ Dawn Stone)Route 44: the kid with his brother's Heracross (→ Never-Melt Ice)

Route 44 → Ice Path: the Cleffa con man (→ Dawn Stone)Ice Path 1F: the Icy Rock duel (→ Icy Rock)

Route 36 gatehouse → Blackthorn City: the runaway Dragonair Trainer (→ Play Rough tutor)Blackthorn City: coaching Crystal (before the Rising Badge; missable)

Dragon's Den: the Elder's trial (the Rising Badge)Dragon Shrine: the Mystery Stone becomes a Charizardite, and the Dragon Rush tutor

Blackthorn City → Route 45: the stolen Badges (→ 3 Energy Powder)Route 45: the rampaging Dragonite (→ Outrage tutor)

Route 46: Team Rocket's dig and Crystal taken hostage (story; romance choice; continues Ilex Forest and Goldenrod City's romance entry)

Route 47: Will, Karen and the Raikou device (story; five battles in a row)Route 48 → Route 47: Gallade, the hurt Buneary and the man afraid of heights (→ Shoal Shell)

Route 48 → Route 47: Gallade, the hurt Buneary and the man afraid of heights (→ Shoal Shell)

Sinjoh Ruins (temple of Arceus): Regigigas and Arceus (after the final Hall of Fame)

Reversal Cave: chase Giovanni through the Distortion World (story; warp-pad maze)

Alto Mare Library (One Island): the legends quiz

Alto Mare Waters: Charmander's owner and the lifeguardAlto Mare Waters → islands → back: the Manaphy Egg

Five Island: the Island Pilgrimage leg (Five Island trials)Five Island: the four-leaf clover (speak up for him)

Four Island: the Mystery Stone buyer (don't sell it)Four Island: small extras (Stone Workshop)

Island Cave (Four Island): Crystal Onix and Granny LisaIsland Cave: small extras

Island Forest (Six Island): before the Lucky Meowth God

One Island: the composer's title → Miracle Seed → TM86 Grass KnotOne Island: the Island Restaurant's battle meals (repeatable)

Ritual Shrine (Seven Island): Giovanni takes the Azure FluteRitual Shrine: borrowing the Azure Flute (post-game; probably unobtainable)

Secret Forest (One Island): Latios, Latias and the Soul Dew

Seven Island: the Island Pilgrimage (start and final trial)Seven Island: the Clamperl pearl scam

Shipyard Ruins (Three Island): the bikers' Chief, a bribe or a fight

Three Island → Six Island: the lost daughter (Three Island's pilgrimage trial)Six Island: the chief's trial and the Fallen Red Star

Sky Pillar Peak: the Four Island trial (Team Rocket takes Rayquaza)Sky Pillar Peak: Rayquaza (post-game, Jade Orb)

Three Island: the Alto Mare Bikers (save the Meowth?)Three Island → Six Island: the lost daughter (Three Island's pilgrimage trial)

Two Island: the old captain's Water-type quiz (→ Piplup)Two Island: a partner for Granny Mae's trial